Deficits in rapid adjustments of movements according to task constraints in Parkinson's disease
Identifieur interne : 003D53 ( Main/Exploration ); précédent : 003D52; suivant : 003D54Deficits in rapid adjustments of movements according to task constraints in Parkinson's disease
Auteurs : Eugene Tunik [États-Unis] ; Sergei V. Adamovich [États-Unis] ; Howard Poizner [États-Unis] ; Anatol G. Feldman [Canada]Source :
- Movement Disorders [ 0885-3185 ] ; 2004-08.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adaptation, Physiological (physiology), Adjustment, Aged, Analysis of Variance, Biomechanical Phenomena, Case-Control Studies, Exercise Movement Techniques (methods), Feedback (physiology), Female, Humans, Male, Middle Aged, Movement (physiology), Nervous system diseases, Parkinson Disease (physiopathology), Parkinson disease, Psychomotor Performance (physiology), Visual Perception (physiology), basal ganglia, frames of reference, multisegmental control, response to perturbation, trajectory formation.
- MESH :
- methods : Exercise Movement Techniques.
- physiology : Adaptation, Physiological, Feedback, Movement, Psychomotor Performance, Visual Perception.
- physiopathology : Parkinson Disease.
- Aged, Analysis of Variance, Biomechanical Phenomena, Case-Control Studies, Female, Humans, Male, Middle Aged.
Abstract
The role of the basal ganglia in the adaptive control of movement was investigated by unexpectedly perturbing movements in 8 patients with Parkinson's disease (PD) tested off medication and in 6 aged‐matched healthy subjects. Subjects performed two movement components simultaneously and without visual feedback: touching the nose with the finger while leaning the trunk forward. Subjects wore a harness connected to an electromagnet, which was attached to a wall. The trunk movement was mechanically blocked in randomly selected trials by engaging the electromagnet. While healthy subjects performed the task equally well in both conditions, PD subjects' hand movements significantly deteriorated in trunk‐perturbed compared to trunk‐free trials. Deteriorated hand movements were characterized by segmented hand paths, unsmooth velocity profiles, and prolonged movement times. This finding indicated that the relatively local trunk perturbation had a global effect on the hand movement of PD subjects, necessitating them to reinitiate, after some delay, their arm movement in perturbed trials. Thus, the basal ganglia may be a critical node in brain networks mediating the flexibility of responses to altered motor states. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20138
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000931
- to stream Istex, to step Curation: 000931
- to stream Istex, to step Checkpoint: 002734
- to stream PubMed, to step Corpus: 003390
- to stream PubMed, to step Curation: 003390
- to stream PubMed, to step Checkpoint: 003501
- to stream Ncbi, to step Merge: 000E94
- to stream Ncbi, to step Curation: 000E94
- to stream Ncbi, to step Checkpoint: 000E94
- to stream Main, to step Merge: 005711
- to stream PascalFrancis, to step Corpus: 002086
- to stream PascalFrancis, to step Curation: 000C35
- to stream PascalFrancis, to step Checkpoint: 002187
- to stream Main, to step Merge: 005A25
- to stream Main, to step Curation: 003D53
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Deficits in rapid adjustments of movements according to task constraints in Parkinson's disease</title><author><name sortKey="Tunik, Eugene" sort="Tunik, Eugene" uniqKey="Tunik E" first="Eugene" last="Tunik">Eugene Tunik</name></author><author><name sortKey="Adamovich, Sergei V" sort="Adamovich, Sergei V" uniqKey="Adamovich S" first="Sergei V." last="Adamovich">Sergei V. Adamovich</name></author><author><name sortKey="Poizner, Howard" sort="Poizner, Howard" uniqKey="Poizner H" first="Howard" last="Poizner">Howard Poizner</name></author><author><name sortKey="Feldman, Anatol G" sort="Feldman, Anatol G" uniqKey="Feldman A" first="Anatol G." last="Feldman">Anatol G. Feldman</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:E060B25FFA3B675D487746C663BAF3A92750983D</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1002/mds.20138</idno><idno type="url">https://api.istex.fr/document/E060B25FFA3B675D487746C663BAF3A92750983D/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000931</idno><idno type="wicri:Area/Istex/Curation">000931</idno><idno type="wicri:Area/Istex/Checkpoint">002734</idno><idno type="wicri:doubleKey">0885-3185:2004:Tunik E:deficits:in:rapid</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:15300654</idno><idno type="wicri:Area/PubMed/Corpus">003390</idno><idno type="wicri:Area/PubMed/Curation">003390</idno><idno type="wicri:Area/PubMed/Checkpoint">003501</idno><idno type="wicri:Area/Ncbi/Merge">000E94</idno><idno type="wicri:Area/Ncbi/Curation">000E94</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E94</idno><idno type="wicri:doubleKey">0885-3185:2004:Tunik E:deficits:in:rapid</idno><idno type="wicri:Area/Main/Merge">005711</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:04-0495243</idno><idno type="wicri:Area/PascalFrancis/Corpus">002086</idno><idno type="wicri:Area/PascalFrancis/Curation">000C35</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">002187</idno><idno type="wicri:doubleKey">0885-3185:2004:Tunik E:deficits:in:rapid</idno><idno type="wicri:Area/Main/Merge">005A25</idno><idno type="wicri:Area/Main/Curation">003D53</idno><idno type="wicri:Area/Main/Exploration">003D53</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Deficits in rapid adjustments of movements according to task constraints in Parkinson's disease</title><author><name sortKey="Tunik, Eugene" sort="Tunik, Eugene" uniqKey="Tunik E" first="Eugene" last="Tunik">Eugene Tunik</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">New Brunswick (New Jersey))</settlement></placeName><orgName type="university">Université Rutgers</orgName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Hampshire</region></placeName><wicri:cityArea>Current Address: Department of Psychological and Brain Sciences, Dartmouth College, Hanover</wicri:cityArea></affiliation></author><author><name sortKey="Adamovich, Sergei V" sort="Adamovich, Sergei V" uniqKey="Adamovich S" first="Sergei V." last="Adamovich">Sergei V. Adamovich</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">New Brunswick (New Jersey))</settlement></placeName><orgName type="university">Université Rutgers</orgName></affiliation></author><author><name sortKey="Poizner, Howard" sort="Poizner, Howard" uniqKey="Poizner H" first="Howard" last="Poizner">Howard Poizner</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">New Brunswick (New Jersey))</settlement></placeName><orgName type="university">Université Rutgers</orgName></affiliation></author><author><name sortKey="Feldman, Anatol G" sort="Feldman, Anatol G" uniqKey="Feldman A" first="Anatol G." last="Feldman">Anatol G. Feldman</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Center for Interdisciplinary Research in Rehabilitation (CRIR), Rehabilitation Institute of Montreal, and Neurological Science Research Center, Department of Physiology, University of Montreal, Montreal, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2004-08">2004-08</date><biblScope unit="vol">19</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="897">897</biblScope><biblScope unit="page" to="906">906</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">E060B25FFA3B675D487746C663BAF3A92750983D</idno><idno type="DOI">10.1002/mds.20138</idno><idno type="ArticleID">MDS20138</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adaptation, Physiological (physiology)</term><term>Adjustment</term><term>Aged</term><term>Analysis of Variance</term><term>Biomechanical Phenomena</term><term>Case-Control Studies</term><term>Exercise Movement Techniques (methods)</term><term>Feedback (physiology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Movement (physiology)</term><term>Nervous system diseases</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson disease</term><term>Psychomotor Performance (physiology)</term><term>Visual Perception (physiology)</term><term>basal ganglia</term><term>frames of reference</term><term>multisegmental control</term><term>response to perturbation</term><term>trajectory formation</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Exercise Movement Techniques</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Adaptation, Physiological</term><term>Feedback</term><term>Movement</term><term>Psychomotor Performance</term><term>Visual Perception</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Analysis of Variance</term><term>Biomechanical Phenomena</term><term>Case-Control Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term><term>Réglage</term><term>Système nerveux pathologie</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The role of the basal ganglia in the adaptive control of movement was investigated by unexpectedly perturbing movements in 8 patients with Parkinson's disease (PD) tested off medication and in 6 aged‐matched healthy subjects. Subjects performed two movement components simultaneously and without visual feedback: touching the nose with the finger while leaning the trunk forward. Subjects wore a harness connected to an electromagnet, which was attached to a wall. The trunk movement was mechanically blocked in randomly selected trials by engaging the electromagnet. While healthy subjects performed the task equally well in both conditions, PD subjects' hand movements significantly deteriorated in trunk‐perturbed compared to trunk‐free trials. Deteriorated hand movements were characterized by segmented hand paths, unsmooth velocity profiles, and prolonged movement times. This finding indicated that the relatively local trunk perturbation had a global effect on the hand movement of PD subjects, necessitating them to reinitiate, after some delay, their arm movement in perturbed trials. Thus, the basal ganglia may be a critical node in brain networks mediating the flexibility of responses to altered motor states. © 2004 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Canada</li><li>États-Unis</li></country><region><li>New Hampshire</li><li>New Jersey</li></region><settlement><li>New Brunswick (New Jersey))</li></settlement><orgName><li>Université Rutgers</li></orgName></list><tree><country name="États-Unis"><region name="New Jersey"><name sortKey="Tunik, Eugene" sort="Tunik, Eugene" uniqKey="Tunik E" first="Eugene" last="Tunik">Eugene Tunik</name></region><name sortKey="Adamovich, Sergei V" sort="Adamovich, Sergei V" uniqKey="Adamovich S" first="Sergei V." last="Adamovich">Sergei V. Adamovich</name><name sortKey="Poizner, Howard" sort="Poizner, Howard" uniqKey="Poizner H" first="Howard" last="Poizner">Howard Poizner</name><name sortKey="Tunik, Eugene" sort="Tunik, Eugene" uniqKey="Tunik E" first="Eugene" last="Tunik">Eugene Tunik</name></country><country name="Canada"><noRegion><name sortKey="Feldman, Anatol G" sort="Feldman, Anatol G" uniqKey="Feldman A" first="Anatol G." last="Feldman">Anatol G. Feldman</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003D53 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003D53 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:E060B25FFA3B675D487746C663BAF3A92750983D
|texte= Deficits in rapid adjustments of movements according to task constraints in Parkinson's disease
}}
| This area was generated with Dilib version V0.6.23. |  |